Overview
C2C12 cells are well-established and commonly used myoblast cell lines for research in skeletal muscle differentiation, growth, and regeneration. These cells have been extensively studied due to their potential for addressing muscle-related diseases and injury, and provide a valuable model for the in vitro analysis of muscle physiology, gene expression, and signaling pathways.Characteristics and Culture
C2C12 cells were originally derived from mouse skeletal muscle in the 1970s and have since become one of the most widely used cell lines in skeletal muscle research. They can be cultured in vitro in regular tissue culture dishes and are relatively easy to maintain. C2C12 cells grow adherently and proliferate rapidly. They can be differentiated into multinucleated myotubes by serum withdrawal, which mimics the process of muscle development in vivo.Applications and Significance
C2C12 cells have been used in diverse fields such as development biology, genetics, and pharmacology research. They have been used to investigate various biological phenomena, including the roles of signaling pathways in muscle differentiation, the regulation of gene expression during myogenesis, and the potential of myoblast transplantation in muscle repair. C2C12 cells have also been used to screen for potential drugs for muscle-related diseases, such as muscular dystrophy. In conclusion, understanding the basics of C2C12 cells is essential for anyone interested in skeletal muscle research. This cell line provides a valuable tool for investigating the complex processes of muscle differentiation, growth, and regeneration. The ability to culture and differentiate C2C12 cells enables researchers to mimic muscle development in vitro and provides insights into fundamental aspects of muscle biology.版权声明：《c2c12细胞（C2C12 Cells Understanding the Basics）》文章主要来源于网络，不代表本网站立场，不承担相关法律责任，如涉及版权问题，请发送邮件至3237157959@qq.com举报，我们会在第一时间进行处理。本文文章链接：http://www.hgkdd.com/hgzl/5040.html
